Natali was born in Detroit, Michigan, to a nursery school teacher/painter mother and a photographer father. He is of Italian and English descent. He moved to Toronto, along with his family, at the age of one. He attended the film programme at Ryerson University. He was eventually hired as a storyboard artist at the Nelvana Animation Studios.
Natali’s directing debut came in 1997, when he was approached to direct Cube (1997). The film became a success worldwide, especially in Japan and France, grossing $15 million in France and breaking box office records for a Canadian film. At the 19th Genie Awards, the film received five nominations and also won the award for Best Canadian First Feature at the Toronto International Film Festival. After this success, Natali went on to direct Cypher (2002) and Nothing (2003).
Following the June 2010 release of Splice (2009), Natali’s next efforts are expected to be an adaptation of J.G. Ballard’s High Rise and a 3D remake of the Wes Craven… read more
Natali's arty direction and Northam's surprising turn in a nebbish role keeps this interesting, but the borrowed (and by now predictable) plot owes much to greater sci-fi writers of yore. Liu is oddly bland and unconvincing in the femme fatale role.