Bruno is a director with no success, and his producer is struggling to set up his next project. He has also recently separated from his wife, with whom he has two children. One day Bruno discovers he has a form of leukemia, and that he requires a donor—he embarks on an unexpected journey of rebirth.

A filmmaker undergoing chemotherapy conjures flashbacks and fantasies from drug-induced reveries in this personal drama from Francesco Brumi. Finding humor and pathos amid moments of artistic introspection, Cosa sarà speaks to the necessity for human connection both in sickness and in health.