Paul attend une transplantation cardiaque. Cristina, ex-junkie, est mère de deux petites filles. Jack sort de prison et redécouvre la foi. A cause d’un accident, ils vont s’affronter, se haïr… et s’aimer.

An impressive follow-up to Amores perros, Iñárritu teamed up with Guillermo Arriaga once again for his English-language debut, complicating the former’s triptych structure in an entwined multi-plot drama. Both Naomi Watts & Benicio del Toro received Oscar® nominations for their riveting performances.